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CA 19-9 assay is to be used as an aid in the management of pancreatic cancer patients in conjunction with other clinical methods. CA 19-9 assay value is frequently elevated in the serum of subjects with various gastrointestinal conditions, such as colorectal, gastric and hepatic carcinomas. A persistent elevation in CA 19-9 assay value following treatment may be indicative of occult metastatic and/or residual disease. No data exist to support the use of CA 19-9 in screening for malignancies.